Prof. Sigal Zilcha-Mano

Head of the Psychotherapy Research Lab

Research areas >>

Full Professor at the Department of Psychology & Data Science Centre, and the Head of the Psychotherapy Research Lab, University of Haifa. 

Prof. Sigal Zilcha-Mano is a worldwide recognized leader in personalized detection and intervention for depression. Her pioneering research leverages the separation of trait-like and state-like processes to achieve precise personalization in mental health treatment. She is a Member of the Israel National Academy of Sciences and a Fellow of the American Psychological Association (APA).

The Psychotherapy Research Lab consists of over 65 researchers, postdocs, and PhD students. The lab develops clinically validated, AI-driven technologies for personalized mental health. By integrating multimodal data from wearables, smartphones, and clinical assessments, the lab models individual-specific trajectories to enable early detection and scalable digital health solutions.

Selected Awards & Recognitions

  • Member, National Academy of Sciences (Israel), 2025.
  • Mid-Career Research Excellence Award, 2024, University of Haifa.

  • Early Career Award 2020, International Society for the Exploration of Psychotherapy Integration (SEPI).

  • Fellow Status 2019, American Psychological Association (APA).

  • Early Career Award 2019, APA Division 29 (Psychotherapy).

  • Editorial Roles: Associate Editor and Editorial Board member for American Psychologist and Journal of Consulting and Clinical Psychology.

Major Research Grants

Prof. Zilcha-Mano has secured over €6.3M in competitive funding from prestigious bodies:

  • ERC Consolidator Grant (2024–2029): Individual-specific understanding of how synchrony becomes curative (€2.12M).
  • ERC Proof of Concept (2025): Proactive Mental Health through Multimodal Smartphone App (€150K).
  • Israel Science Foundation (ISF): Mechanisms of change in psychotherapy research for depression.
  • United States-Israel Binational Science Foundation (BSF): Manipulating visit frequency to understand placebo effects in depression (€200,000).
  • National Institute for Psychobiology (2023–2025) – Neural mechanisms of expectancy effect in psychotherapy for MDD (€33,500)

Prof. Sigal Zilcha-Mano

Head of the Psychotherapy Research Lab

Research areas >>

Full Professor at the Department of Psychology & Data Science Centre, and the Head of the Psychotherapy Research Lab, University of Haifa. 

Prof. Sigal Zilcha-Mano is a worldwide recognized leader in personalized detection and intervention for depression. Her pioneering research leverages the separation of trait-like and state-like processes to achieve precise personalization in mental health treatment. She is a Member of the Israel National Academy of Sciences and a Fellow of the American Psychological Association (APA).

The Psychotherapy Research Lab consists of over 65 researchers, postdocs, and PhD students. The lab develops clinically validated, AI-driven technologies for personalized mental health. By integrating multimodal data from wearables, smartphones, and clinical assessments, the lab models individual-specific trajectories to enable early detection and scalable digital health solutions.

Selected Awards & Recognitions

  • Member, National Academy of Sciences (Israel), 2025.
  • Mid-Career Research Excellence Award, 2024, University of Haifa.

  • Early Career Award 2020, International Society for the Exploration of Psychotherapy Integration (SEPI).

  • Fellow Status 2019, American Psychological Association (APA).

  • Early Career Award 2019, APA Division 29 (Psychotherapy).

  • Editorial Roles: Associate Editor and Editorial Board member for American Psychologist and Journal of Consulting and Clinical Psychology.

Major Research Grants

Prof. Zilcha-Mano has secured over €6.3M in competitive funding from prestigious bodies:

  • ERC Consolidator Grant (2024–2029): Individual-specific understanding of how synchrony becomes curative (€2.12M).
  • ERC Proof of Concept (2025): Proactive Mental Health through Multimodal Smartphone App (€150K).
  • Israel Science Foundation (ISF): Mechanisms of change in psychotherapy research for depression.
  • United States-Israel Binational Science Foundation (BSF): Manipulating visit frequency to understand placebo effects in depression (€200,000).
  • National Institute for Psychobiology (2023–2025) – Neural mechanisms of expectancy effect in psychotherapy for MDD (€33,500)