{"id":2773,"date":"2026-01-13T08:02:17","date_gmt":"2026-01-13T08:02:17","guid":{"rendered":"https:\/\/carmel-ltd.haifa.ac.il\/?post_type=researchers&#038;p=2773"},"modified":"2026-02-04T15:03:57","modified_gmt":"2026-02-04T15:03:57","slug":"prof-sigal-zilcha-mano","status":"publish","type":"researchers","link":"https:\/\/carmel-ltd.haifa.ac.il\/?researchers=prof-sigal-zilcha-mano","title":{"rendered":"Prof. Sigal Zilcha-Mano"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2773\" class=\"elementor elementor-2773\" data-elementor-post-type=\"researchers\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a2b3a7c e-flex e-con-boxed e-con e-parent\" data-id=\"a2b3a7c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9c3f84e elementor-hidden-mobile elementor-widget elementor-widget-spacer\" data-id=\"9c3f84e\" 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srcset=\"https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/uploads\/2026\/01\/Dr-Sigal-Zilcha-Mano-scaled-1-818x1024.jpg 818w, https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/uploads\/2026\/01\/Dr-Sigal-Zilcha-Mano-scaled-1-240x300.jpg 240w, https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/uploads\/2026\/01\/Dr-Sigal-Zilcha-Mano-scaled-1-768x961.jpg 768w, https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/uploads\/2026\/01\/Dr-Sigal-Zilcha-Mano-scaled-1-1228x1536.jpg 1228w, https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/uploads\/2026\/01\/Dr-Sigal-Zilcha-Mano-scaled-1.jpg 1366w\" sizes=\"(max-width: 818px) 100vw, 818px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5dcc14a e-con-full e-flex e-con e-child\" data-id=\"5dcc14a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4c20d10 elementor-widget elementor-widget-heading\" data-id=\"4c20d10\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Prof. Sigal Zilcha-Mano<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b83be35 elementor-widget elementor-widget-ucaddon_social_icons_glare_effect\" data-id=\"b83be35\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"ucaddon_social_icons_glare_effect.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<!-- start Social Icons Glare Effect -->\n\t\t<link id='font-awesome-css' href='https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/plugins\/unlimited-elements-for-elementor-premium\/assets_libraries\/font-awesome6\/fontawesome-all.min.css' type='text\/css' rel='stylesheet' >\n\t\t<link id='font-awesome-4-shim-css' href='https:\/\/carmel-ltd.haifa.ac.il\/wp-content\/plugins\/unlimited-elements-for-elementor-premium\/assets_libraries\/font-awesome6\/fontawesome-v4-shims.min.css' type='text\/css' rel='stylesheet' >\n\n<style>\/* widget: Social Icons Glare Effect *\/\n\n#uc_social_icons_glare_effect_elementor_b83be35 *{\n\n\tbox-sizing: border-box;\n}\n\n#uc_social_icons_glare_effect_elementor_b83be35{\n\tposition:relative;\n\twidth:100%;\n}\n\n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button {\n    box-shadow: 0 0 30px 0 rgba(0, 0, 0, 0.05);\n    display: inline-block;\n    opacity: 1;\n    overflow: hidden;\n    position: relative;\n    text-align: center;\n    transition: all 0.35s cubic-bezier(0.31, -0.105, 0.43, 1.59) 0s;\n    \n}\n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button::before {\n    content: \"\";\n    height: 100%;\n    left: 0%;\n    position: absolute;\n    top: 100%;\n    transition: all 0.35s;\n    width: 100%;\n}\n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button i {\n    transform: scale(0.8);\n    transition: all 0.35s cubic-bezier(0.31, -0.105, 0.43, 1.59) 0s;\n    vertical-align: middle;\n}\n\n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button:focus::before, \n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button:hover::before {\n    left: 0%;\n    top: 0%;\n}\n\n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button i {\n\tcolor:#FFFFFF;\n}\n\n#uc_social_icons_glare_effect_elementor_b83be35 .uc_social-button:hover i {\n\tcolor:#A1F8FD;\n}\n\n<\/style>\n\n<div class=\"uc_stylish_social_buttons\" id=\"uc_social_icons_glare_effect_elementor_b83be35\"> \n    <!--uc_container_holder--> \n    <div class=\"uc_social-buttons\">\n    \t<a href=\"https:\/\/psychotherapy.haifa.ac.il\/?lang=en\" class=\"uc_social-button\"   target='_blank'><i class=\"fas fa-globe\"><\/i><\/a>\n<a href=\"https:\/\/www.facebook.com\/depressionhaifa\/?ref=page_internal\" class=\"uc_social-button\"  ><i class=\"fab fa-facebook-f\"><\/i><\/a>\n\n    <\/div>\n<\/div>\n<!-- end Social Icons Glare Effect -->\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e60bdb elementor-widget elementor-widget-heading\" data-id=\"2e60bdb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Head of the Psychotherapy Research Lab <\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a3e452 elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" data-id=\"2a3e452\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<a href=\"mailto:depressionpsychotherapy@gmail.com\" class=\"elementor-icon elementor-animation-grow\" tabindex=\"-1\" aria-label=\"depressionpsychotherapy@gmail.com\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M464 64H48C21.49 64 0 85.49 0 112v288c0 26.51 21.49 48 48 48h416c26.51 0 48-21.49 48-48V112c0-26.51-21.49-48-48-48zm0 48v40.805c-22.422 18.259-58.168 46.651-134.587 106.49-16.841 13.247-50.201 45.072-73.413 44.701-23.208.375-56.579-31.459-73.413-44.701C106.18 199.465 70.425 171.067 48 152.805V112h416zM48 400V214.398c22.914 18.251 55.409 43.862 104.938 82.646 21.857 17.205 60.134 55.186 103.062 54.955 42.717.231 80.509-37.199 103.053-54.947 49.528-38.783 82.032-64.401 104.947-82.653V400H48z\"><\/path><\/svg>\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<a href=\"mailto:depressionpsychotherapy@gmail.com\" >\n\t\t\t\t\t\t\tdepressionpsychotherapy@gmail.com\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6ab929f elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" data-id=\"6ab929f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<a href=\"mailto:sigalzil@gmail.com\" class=\"elementor-icon elementor-animation-grow\" tabindex=\"-1\" aria-label=\"sigalzil@gmail.com\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M464 64H48C21.49 64 0 85.49 0 112v288c0 26.51 21.49 48 48 48h416c26.51 0 48-21.49 48-48V112c0-26.51-21.49-48-48-48zm0 48v40.805c-22.422 18.259-58.168 46.651-134.587 106.49-16.841 13.247-50.201 45.072-73.413 44.701-23.208.375-56.579-31.459-73.413-44.701C106.18 199.465 70.425 171.067 48 152.805V112h416zM48 400V214.398c22.914 18.251 55.409 43.862 104.938 82.646 21.857 17.205 60.134 55.186 103.062 54.955 42.717.231 80.509-37.199 103.053-54.947 49.528-38.783 82.032-64.401 104.947-82.653V400H48z\"><\/path><\/svg>\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<a href=\"mailto:sigalzil@gmail.com\" >\n\t\t\t\t\t\t\tsigalzil@gmail.com\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5198942 elementor-widget elementor-widget-ucaddon_toggle_text_button\" data-id=\"5198942\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"ucaddon_toggle_text_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<!-- start Toggle Text Button -->\n<style>\/* widget: Toggle Text Button *\/\n\n#uc_toggle_text_button_elementor_5198942 .read_more{\n  text-decoration:none;\n  font-size:14px;\n  color:white;\n  transition:0.3s;\n  cursor: pointer;\n}\n\n<\/style>\n\n<div id=\"uc_toggle_text_button_elementor_5198942\" class=\"toggle_text_button\"> \n  \n  <div class=\"short_txt\"><\/div>   \n  <div class=\"long_txt\" style=\"display:none;\"><h3><span style=\"color: #a1f8fd;\">Research areas:<\/span><\/h3><ul><li><span style=\"text-decoration: underline;\"><strong>Large-scale multimodal capability:<\/strong> <\/span>Integration of physiological, behavioral, acoustic, motion, facial expression, and wearable data across thousands of clinically assessed psychotherapy sessions.<\/li><li><span style=\"text-decoration: underline;\"><strong>Clinically grounded and innovative personalization:<\/strong><\/span> Gold-standard calibration using HDRS and other structured clinical interviews, with innovative separation of trait-like differences and state-like processes.<\/li><li><span style=\"text-decoration: underline;\"><strong>Proven AI readiness:<\/strong><\/span> Decades of validated biomarkers, over 1,000 observations of clinical- and smartphone-based data, and machine-learning models trained on real-world clinical populations.<\/li><li><span style=\"text-decoration: underline;\"><strong>Strong industry &amp; translational experience:<\/strong><\/span> Extensive experience translating academic innovation into proof-of-concept systems aligned with real-world deployment constraints.<\/li><\/ul><\/div>  \n  \n  <div style=\"text-align:inherit;\">  \n    <span class=\"read_more\">\n      <span class=\"btn_txt_before_click\"><span  class=\"uc_style_toggle_text_button_elementor_button_text\" style=\"color:#1F3343;\">Research areas >><\/span><\/span>\n      <span class=\"btn_txt_after_click\" style=\"display:none;\"><span  class=\"uc_style_toggle_text_button_elementor_button_text_close\" style=\"color:#1F3343;\">Show Less<\/span><\/span>\n    <\/span>  \n  <\/div>  \n<\/div>\n<!-- end Toggle Text Button -->\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b8d2390 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"b8d2390\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd668c4 elementor-widget elementor-widget-text-editor\" data-id=\"cd668c4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span data-path-to-node=\"4,0\"><span class=\"citation-108\">Full Professor at the Department of Psychology &amp; Data Science Centre, and the <\/span><\/span><span data-path-to-node=\"4,3\"><span class=\"citation-107\">Head of the Psychotherapy Research Lab, University of Haifa.\u00a0<\/span><\/span><\/p><p><span data-path-to-node=\"5,1\"><span class=\"citation-106\">Prof. Sigal Zilcha-Mano is a worldwide recognized leader in personalized detection and intervention for depression<\/span><\/span><span data-path-to-node=\"5,3\">. <\/span><span data-path-to-node=\"5,5\"><span class=\"citation-105\">Her pioneering research leverages the separation of trait-like and state-like processes to achieve precise personalization in mental health treatment<\/span><\/span><span data-path-to-node=\"5,7\">. <\/span><span data-path-to-node=\"5,9\"><span class=\"citation-104\">She is a Member of the Israel National Academy of Sciences and a Fellow of the American Psychological Association (APA)<\/span><\/span><span data-path-to-node=\"5,11\">.<\/span><\/p><p><span data-path-to-node=\"7,1\"><span class=\"citation-103\">The Psychotherapy Research Lab consists of over 65 researchers, postdocs, and PhD students<\/span><\/span><span data-path-to-node=\"7,3\">. <\/span><span data-path-to-node=\"7,5\"><span class=\"citation-102\">The lab develops clinically validated, AI-driven technologies for personalized mental health<\/span><\/span><span data-path-to-node=\"7,7\">. <\/span><span data-path-to-node=\"7,9\"><span class=\"citation-101\">By integrating multimodal data from wearables, smartphones, and clinical assessments, the lab models individual-specific trajectories to enable early detection and scalable digital health solutions<\/span><\/span><span data-path-to-node=\"7,11\">.<\/span><\/p><p><span style=\"text-decoration: underline;\"><strong>Selected Awards &amp; Recognitions<\/strong><\/span><\/p><ul><li data-path-to-node=\"10,0,1\"><span data-path-to-node=\"10,0,1,0\"><b data-path-to-node=\"10,0,1,0\" data-index-in-node=\"0\"><span class=\"citation-96\">Member, National Academy of Sciences (Israel), 2025.<\/span><\/b><\/span><\/li><li><p data-path-to-node=\"10,1,1\"><span data-path-to-node=\"10,1,1,0\"><b data-path-to-node=\"10,1,1,0\" data-index-in-node=\"0\"><span class=\"citation-95\">Mid-Career Research Excellence Award, 2024<\/span><\/b><span class=\"citation-95\">, University of Haifa.<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,2,1\"><span data-path-to-node=\"10,2,1,0\"><b data-path-to-node=\"10,2,1,0\" data-index-in-node=\"0\"><span class=\"citation-94\">Early Career Award 2020<\/span><\/b><span class=\"citation-94\">, International Society for the Exploration of Psychotherapy Integration (SEPI).<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,3,1\"><span data-path-to-node=\"10,3,1,0\"><b data-path-to-node=\"10,3,1,0\" data-index-in-node=\"0\"><span class=\"citation-93\">Fellow Status 2019<\/span><\/b><span class=\"citation-93\">, American Psychological Association (APA).<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,4,1\"><span data-path-to-node=\"10,4,1,0\"><b data-path-to-node=\"10,4,1,0\" data-index-in-node=\"0\"><span class=\"citation-92\">Early Career Award 2019<\/span><\/b><span class=\"citation-92\">, APA Division 29 (Psychotherapy).<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,5,1\"><span data-path-to-node=\"10,5,1,0\"><b data-path-to-node=\"10,5,1,0\" data-index-in-node=\"0\"><span class=\"citation-91\">Editorial Roles:<\/span><\/b><span class=\"citation-91\"> Associate Editor and Editorial Board member for <\/span><i data-path-to-node=\"10,5,1,0\" data-index-in-node=\"65\"><span class=\"citation-91\">American Psychologist<\/span><\/i><span class=\"citation-91\"> and <\/span><i data-path-to-node=\"10,5,1,0\" data-index-in-node=\"91\"><span class=\"citation-91\">Journal of Consulting and Clinical Psychology<\/span><\/i><\/span><span data-path-to-node=\"10,5,1,2\">.<\/span><\/p><\/li><\/ul><p><span style=\"text-decoration: underline;\"><strong>Major Research Grants<\/strong><\/span><\/p><p data-path-to-node=\"12\"><span data-path-to-node=\"12,1\"><span class=\"citation-90\">Prof. Zilcha-Mano has secured over \u20ac6.3M in competitive funding from prestigious bodies<\/span><\/span><span data-path-to-node=\"12,3\">:<\/span><\/p><ul><li data-path-to-node=\"13,0,1\"><span data-path-to-node=\"13,0,1,0\"><b data-path-to-node=\"13,0,1,0\" data-index-in-node=\"0\"><span class=\"citation-89\">ERC Consolidator Grant (2024\u20132029):<\/span><\/b><span class=\"citation-89\"> Individual-specific understanding of how synchrony becomes curative (\u20ac2.12M)<\/span><\/span><span data-path-to-node=\"13,0,1,2\">.<\/span><\/li><li data-path-to-node=\"13,1,1\"><span data-path-to-node=\"13,1,1,0\"><b data-path-to-node=\"13,1,1,0\" data-index-in-node=\"0\"><span class=\"citation-88\">ERC Proof of Concept (2025):<\/span><\/b><span class=\"citation-88\"> Proactive Mental Health through Multimodal Smartphone App (\u20ac150K)<\/span><\/span><span data-path-to-node=\"13,1,1,2\">.<\/span><\/li><li data-path-to-node=\"13,2,1\"><span data-path-to-node=\"13,2,1,0\"><b data-path-to-node=\"13,2,1,0\" data-index-in-node=\"0\"><span class=\"citation-87\">Israel Science Foundation (ISF):<\/span><\/b><span class=\"citation-87\"> Mechanisms of change in psychotherapy research for depression<\/span><\/span><span data-path-to-node=\"13,2,1,2\">.<\/span><\/li><li data-path-to-node=\"13,3,1\"><span data-path-to-node=\"13,3,1,0\"><b data-path-to-node=\"13,3,1,0\" data-index-in-node=\"0\"><span class=\"citation-86\"><strong>United States-Israel Binational Science Foundation (<\/strong>BSF):<\/span><\/b><span class=\"citation-86\"> Manipulating visit frequency to understand placebo effects in depression (\u20ac200,000).<\/span><\/span><\/li><li><strong>National Institute for Psychobiology (2023\u20132025)<\/strong> \u2013 Neural mechanisms of expectancy effect in psychotherapy for MDD (\u20ac33,500)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5e29033 e-flex e-con-boxed e-con e-parent\" data-id=\"5e29033\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ec9be7f elementor-hidden-desktop elementor-hidden-tablet e-con-full e-flex e-con e-child\" data-id=\"ec9be7f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-4f2d887 e-con-full e-transform e-flex e-con e-child\" data-id=\"4f2d887\" data-element_type=\"container\" data-e-type=\"container\" 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data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Prof. Sigal Zilcha-Mano<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4117740 elementor-widget elementor-widget-heading\" data-id=\"4117740\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Head of the Psychotherapy Research Lab <\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6ada090 elementor-position-inline-start elementor-mobile-position-inline-start elementor-view-default elementor-widget elementor-widget-icon-box\" data-id=\"6ada090\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-box.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-box-wrapper\">\n\n\t\t\t\t\t\t<div class=\"elementor-icon-box-icon\">\n\t\t\t\t<a href=\"mailto:sigalzil@gmail.com\" 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48-48V112c0-26.51-21.49-48-48-48zm0 48v40.805c-22.422 18.259-58.168 46.651-134.587 106.49-16.841 13.247-50.201 45.072-73.413 44.701-23.208.375-56.579-31.459-73.413-44.701C106.18 199.465 70.425 171.067 48 152.805V112h416zM48 400V214.398c22.914 18.251 55.409 43.862 104.938 82.646 21.857 17.205 60.134 55.186 103.062 54.955 42.717.231 80.509-37.199 103.053-54.947 49.528-38.783 82.032-64.401 104.947-82.653V400H48z\"><\/path><\/svg>\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<a href=\"mailto:depressionpsychotherapy@gmail.com\" >\n\t\t\t\t\t\t\tdepressionpsychotherapy@gmail.com\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1406587 elementor-widget elementor-widget-ucaddon_social_icons_glare_effect\" data-id=\"1406587\" data-element_type=\"widget\" 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href=\"https:\/\/www.facebook.com\/depressionhaifa\/?ref=page_internal\" class=\"uc_social-button\"   target='_blank'><i class=\"fab fa-facebook-f\"><\/i><\/a>\n\n    <\/div>\n<\/div>\n<!-- end Social Icons Glare Effect -->\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c2a9317 elementor-widget elementor-widget-ucaddon_toggle_text_button\" data-id=\"c2a9317\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"ucaddon_toggle_text_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<!-- start Toggle Text Button -->\n<style>\/* widget: Toggle Text Button *\/\n\n#uc_toggle_text_button_elementor_c2a9317 .read_more{\n  text-decoration:none;\n  font-size:14px;\n  color:white;\n  transition:0.3s;\n  cursor: pointer;\n}\n\n<\/style>\n\n<div id=\"uc_toggle_text_button_elementor_c2a9317\" class=\"toggle_text_button\"> \n  \n  <div class=\"short_txt\"><\/div>   \n  <div class=\"long_txt\" style=\"display:none;\"><h3><span style=\"color: #a1f8fd;\">Research areas:<\/span><\/h3><ul><li><span style=\"text-decoration: underline;\"><strong>Large-scale multimodal capability:<\/strong> <\/span>Integration of physiological, behavioral, acoustic, motion, facial expression, and wearable data across thousands of clinically assessed psychotherapy sessions.<\/li><li><span style=\"text-decoration: underline;\"><strong>Clinically grounded and innovative personalization:<\/strong><\/span> Gold-standard calibration using HDRS and other structured clinical interviews, with innovative separation of trait-like differences and state-like processes.<\/li><li><span style=\"text-decoration: underline;\"><strong>Proven AI readiness:<\/strong><\/span> Decades of validated biomarkers, over 1,000 observations of clinical- and smartphone-based data, and machine-learning models trained on real-world clinical populations.<\/li><li><span style=\"text-decoration: underline;\"><strong>Strong industry &amp; translational experience:<\/strong><\/span> Extensive experience translating academic innovation into proof-of-concept systems aligned with real-world deployment constraints.<\/li><\/ul><\/div>  \n  \n  <div style=\"text-align:inherit;\">  \n    <span class=\"read_more\">\n      <span class=\"btn_txt_before_click\"><span  class=\"uc_style_toggle_text_button_elementor_button_text\" style=\"color:#1F3343;\">Research areas >><\/span><\/span>\n      <span class=\"btn_txt_after_click\" style=\"display:none;\"><span  class=\"uc_style_toggle_text_button_elementor_button_text_close\" style=\"color:#1F3343;\">Show Less<\/span><\/span>\n    <\/span>  \n  <\/div>  \n<\/div>\n<!-- end Toggle Text Button -->\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0dc953b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"0dc953b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b8693ee elementor-widget elementor-widget-text-editor\" data-id=\"b8693ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span data-path-to-node=\"4,0\"><span class=\"citation-108\">Full Professor at the Department of Psychology &amp; Data Science Centre, and the <\/span><\/span><span data-path-to-node=\"4,3\"><span class=\"citation-107\">Head of the Psychotherapy Research Lab, University of Haifa.\u00a0<\/span><\/span><\/p><p><span data-path-to-node=\"5,1\"><span class=\"citation-106\">Prof. Sigal Zilcha-Mano is a worldwide recognized leader in personalized detection and intervention for depression<\/span><\/span><span data-path-to-node=\"5,3\">. <\/span><span data-path-to-node=\"5,5\"><span class=\"citation-105\">Her pioneering research leverages the separation of trait-like and state-like processes to achieve precise personalization in mental health treatment<\/span><\/span><span data-path-to-node=\"5,7\">. <\/span><span data-path-to-node=\"5,9\"><span class=\"citation-104\">She is a Member of the Israel National Academy of Sciences and a Fellow of the American Psychological Association (APA)<\/span><\/span><span data-path-to-node=\"5,11\">.<\/span><\/p><p><span data-path-to-node=\"7,1\"><span class=\"citation-103\">The Psychotherapy Research Lab consists of over 65 researchers, postdocs, and PhD students<\/span><\/span><span data-path-to-node=\"7,3\">. <\/span><span data-path-to-node=\"7,5\"><span class=\"citation-102\">The lab develops clinically validated, AI-driven technologies for personalized mental health<\/span><\/span><span data-path-to-node=\"7,7\">. <\/span><span data-path-to-node=\"7,9\"><span class=\"citation-101\">By integrating multimodal data from wearables, smartphones, and clinical assessments, the lab models individual-specific trajectories to enable early detection and scalable digital health solutions<\/span><\/span><span data-path-to-node=\"7,11\">.<\/span><\/p><p><span style=\"text-decoration: underline;\"><strong>Selected Awards &amp; Recognitions<\/strong><\/span><\/p><ul><li data-path-to-node=\"10,0,1\"><span data-path-to-node=\"10,0,1,0\"><b data-path-to-node=\"10,0,1,0\" data-index-in-node=\"0\"><span class=\"citation-96\">Member, National Academy of Sciences (Israel), 2025.<\/span><\/b><\/span><\/li><li><p data-path-to-node=\"10,1,1\"><span data-path-to-node=\"10,1,1,0\"><b data-path-to-node=\"10,1,1,0\" data-index-in-node=\"0\"><span class=\"citation-95\">Mid-Career Research Excellence Award, 2024<\/span><\/b><span class=\"citation-95\">, University of Haifa.<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,2,1\"><span data-path-to-node=\"10,2,1,0\"><b data-path-to-node=\"10,2,1,0\" data-index-in-node=\"0\"><span class=\"citation-94\">Early Career Award 2020<\/span><\/b><span class=\"citation-94\">, International Society for the Exploration of Psychotherapy Integration (SEPI).<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,3,1\"><span data-path-to-node=\"10,3,1,0\"><b data-path-to-node=\"10,3,1,0\" data-index-in-node=\"0\"><span class=\"citation-93\">Fellow Status 2019<\/span><\/b><span class=\"citation-93\">, American Psychological Association (APA).<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,4,1\"><span data-path-to-node=\"10,4,1,0\"><b data-path-to-node=\"10,4,1,0\" data-index-in-node=\"0\"><span class=\"citation-92\">Early Career Award 2019<\/span><\/b><span class=\"citation-92\">, APA Division 29 (Psychotherapy).<\/span><\/span><\/p><\/li><li><p data-path-to-node=\"10,5,1\"><span data-path-to-node=\"10,5,1,0\"><b data-path-to-node=\"10,5,1,0\" data-index-in-node=\"0\"><span class=\"citation-91\">Editorial Roles:<\/span><\/b><span class=\"citation-91\"> Associate Editor and Editorial Board member for <\/span><i data-path-to-node=\"10,5,1,0\" data-index-in-node=\"65\"><span class=\"citation-91\">American Psychologist<\/span><\/i><span class=\"citation-91\"> and <\/span><i data-path-to-node=\"10,5,1,0\" data-index-in-node=\"91\"><span class=\"citation-91\">Journal of Consulting and Clinical Psychology<\/span><\/i><\/span><span data-path-to-node=\"10,5,1,2\">.<\/span><\/p><\/li><\/ul><p><span style=\"text-decoration: underline;\"><strong>Major Research Grants<\/strong><\/span><\/p><p data-path-to-node=\"12\"><span data-path-to-node=\"12,1\"><span class=\"citation-90\">Prof. Zilcha-Mano has secured over \u20ac6.3M in competitive funding from prestigious bodies<\/span><\/span><span data-path-to-node=\"12,3\">:<\/span><\/p><ul><li data-path-to-node=\"13,0,1\"><span data-path-to-node=\"13,0,1,0\"><b data-path-to-node=\"13,0,1,0\" data-index-in-node=\"0\"><span class=\"citation-89\">ERC Consolidator Grant (2024\u20132029):<\/span><\/b><span class=\"citation-89\"> Individual-specific understanding of how synchrony becomes curative (\u20ac2.12M)<\/span><\/span><span data-path-to-node=\"13,0,1,2\">.<\/span><\/li><li data-path-to-node=\"13,1,1\"><span data-path-to-node=\"13,1,1,0\"><b data-path-to-node=\"13,1,1,0\" data-index-in-node=\"0\"><span class=\"citation-88\">ERC Proof of Concept (2025):<\/span><\/b><span class=\"citation-88\"> Proactive Mental Health through Multimodal Smartphone App (\u20ac150K)<\/span><\/span><span data-path-to-node=\"13,1,1,2\">.<\/span><\/li><li data-path-to-node=\"13,2,1\"><span data-path-to-node=\"13,2,1,0\"><b data-path-to-node=\"13,2,1,0\" data-index-in-node=\"0\"><span class=\"citation-87\">Israel Science Foundation (ISF):<\/span><\/b><span class=\"citation-87\"> Mechanisms of change in psychotherapy research for depression<\/span><\/span><span data-path-to-node=\"13,2,1,2\">.<\/span><\/li><li data-path-to-node=\"13,3,1\"><span data-path-to-node=\"13,3,1,0\"><b data-path-to-node=\"13,3,1,0\" data-index-in-node=\"0\"><span class=\"citation-86\"><strong>United States-Israel Binational Science Foundation (<\/strong>BSF):<\/span><\/b><span class=\"citation-86\"> Manipulating visit frequency to understand placebo effects in depression (\u20ac200,000).<\/span><\/span><\/li><li><strong>National Institute for Psychobiology (2023\u20132025)<\/strong> \u2013 Neural mechanisms of expectancy effect in psychotherapy for MDD (\u20ac33,500)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6eebf34 e-flex e-con-boxed e-con e-parent\" data-id=\"6eebf34\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-253015f elementor-widget elementor-widget-spacer\" data-id=\"253015f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Research Areas:<br \/>\nArtificial Intelligence<br \/>\nMedical Applications<br \/>\nPsychology<\/p>\n","protected":false},"featured_media":2824,"template":"elementor_header_footer","tags":[18,10],"class_list":["post-2773","researchers","type-researchers","status-publish","has-post-thumbnail","hentry","tag-medical-applications","tag-artificial-inteligence","entry","has-media"],"acf":[],"_links":{"self":[{"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/researchers\/2773","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/researchers"}],"about":[{"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/types\/researchers"}],"version-history":[{"count":50,"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/researchers\/2773\/revisions"}],"predecessor-version":[{"id":5057,"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/researchers\/2773\/revisions\/5057"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=\/wp\/v2\/media\/2824"}],"wp:attachment":[{"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2773"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/carmel-ltd.haifa.ac.il\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2773"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}